Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5535967 | 0.89 | TAAR1 (0.46) | TAAR1HPGDDRD2DRD3SLC1A3 | |
| SCHEMBL5541802 | 0.87 | TAAR1 (0.44) | TAAR1HPGDDRD2DRD3SLC1A3 | |
| SCHEMBL5541464 | 0.86 | TAAR1 (0.43) | TAAR1HPGDDRD2DRD3SLC1A3 | |
| SCHEMBL5544151 | 0.86 | TAAR1 (0.43) | TAAR1HPGDDRD2DRD3SLC1A3 | |
| SCHEMBL7686942 | 0.81 | TAAR1 (0.48) | TAAR1HPGDDRD2DRD3SLC1A3 | |
| SCHEMBL5541959 | 0.80 | — | — | |
| SCHEMBL29009267 | 0.79 | TAAR1 (0.47) | TAAR1HPGDDRD2DRD3SLC1A3 | |
| Hydrochloric Acid SCHEMBL28198042 | 0.78 | SLC1A3 (0.46) | TAAR1HPGDDRD2DRD3SLC1A3 | |
| SCHEMBL25386744 | 0.74 | — | — | |
| SCHEMBL8256108 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109912621-A | A kind of asymmetric naphthalene core small molecule receptor material and its preparation method and application | 湖南科技大学 | 2019-06-21 | — | — | CN | claimed |
| CN-109776567-A | A kind of hexa-atomic bridged ring pyrene core small molecule receptor material and its preparation method and application | 湖南科技大学 | 2019-05-21 | — | — | CN | claimed |
| CN-109776568-A | Axisymmetric hexa-atomic bridged ring naphthalene core small molecule receptor material of one kind and its preparation method and application | 湖南科技大学 | 2019-05-21 | — | — | CN | claimed |
| CN-104703992-B | Process for preparing thienopyrimidine derivatives | 武田药品工业株式会社 | 2019-03-05 | — | — | CN | claimed |
| CN-109053766-A | The preparation method of Thienopyrimidine derivative | 武田药品工业株式会社 | 2018-12-21 | — | — | CN | claimed |
| CN-106366095-A | Polycyclic-based field effect transistor material and preparation method and application thereof | 苏州大学 | 2017-02-01 | — | — | CN | claimed |
| CN-102924429-B | 1,2-naphthaquinone derivatives and preparation method thereof | UNIV XINXIANG MEDICAL | 2013-12-11 | — | — | CN | claimed |
| CN-103242290-A | Preparation method of 6-tert-butyl-4,5,6,7-tetrahydrobenzothiophene-2-amine | KEJIE BIO SUZHOU PHARMACEUTICAL CO LTD | 2013-08-14 | — | — | CN | claimed |
| CN-102924429-A | 1,2-naphthaquinone derivatives and preparation method thereof | UNIV XINXIANG MEDICAL | 2013-02-13 | — | — | CN | claimed |
| CN-101857588-A | 4-aromatic aminoquinazoline derivative and purpose thereof | UNIV SOUTHEAST | 2010-10-13 | — | — | CN | claimed |
| CN-110475776-A | For preventing and treating the tricyclic carboxylic acid amides of arthropod | BAYER CROPSCIENCE AG | 2019-11-19 | — | — | CN | disclosed |
| CN-110115365-A | The adjusting that actinism receptor and relative ligand are carried out | 西诺米克斯公司 | 2019-08-13 | — | — | CN | disclosed |
| CN-109970760-A | ACC inhibitor and its purposes | 吉利德阿波罗公司 | 2019-07-05 | — | — | CN | disclosed |
| CN-109912621-A | A kind of asymmetric naphthalene core small molecule receptor material and its preparation method and application | 湖南科技大学 | 2019-06-21 | — | — | CN | disclosed |
| CN-106905346-B | ACC inhibitor and its purposes | 吉利德阿波罗公司 | 2019-05-28 | — | — | CN | disclosed |
| CN-1522258-A | Novel 4-amino-5, 6-substituted thieno [2, 3-D ] pyrimidine compounds | — | 2004-08-18 | — | — | CN | disclosed |
| CN-1489458-A | Inflammatory cytokine production dissociation inhibitor | ��ʽ����ҽҩ��������о��� | 2004-04-14 | — | — | CN | disclosed |
| CN-1422265-A | Process for producing benzo-fused heterocycle | MERCK PATENT GMBH (DE) | 2003-06-04 | — | — | CN | disclosed |
| CN-1335777-A | Preventives or remedies for myocarditis, dilated cardiomyopathy and cardiac insufficiency containing NF-K B inhibitors as the active ingredient | SUNTORY LTD (JP) | 2002-02-13 | — | — | CN | disclosed |
| CN-1228701-A | Heterocyclic compounds with thrombolytic activity and their use for treating thrombosis | DUPIN JEAN PIERRE (FR) | 1999-09-15 | — | — | CN | disclosed |