Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 17/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27502159 | 0.92 | REN (0.48) | REN | |
| SCHEMBL7081975 | 0.92 | REN (0.45) | REN | |
| SCHEMBL27502528 | 0.92 | REN (0.49) | REN | |
| SCHEMBL28740422 | 0.92 | REN (0.46) | REN | |
| SCHEMBL27487490 | 0.91 | REN (0.56) | REN | |
| SCHEMBL27555324 | 0.90 | REN (0.45) | REN | |
| SCHEMBL27487145 | 0.88 | REN (0.45) | REN | |
| SCHEMBL27488575 | 0.86 | REN (0.44) | REN | |
| SCHEMBL27503271 | 0.86 | REN (0.52) | REN | |
| SCHEMBL7075968 | 0.85 | REN (0.50) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1256326-C | Novel 4- (oxoxyphenyl) -3-oxopiperidines for the treatment of cardiac and renal insufficiency | HOFFMANN LA ROCHE (CH) | 2006-05-17 | — | — | CN | disclosed |
| CN-1202152-A | Novel 4- (oxoxyphenyl) -3-oxopiperidines for the treatment of cardiac and renal insufficiency | HOFFMANN LA ROCHE (CH) | 1998-12-16 | — | — | CN | disclosed |