Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057318 | 0.91 | HDAC6 (0.48) | CA1CA2CHRM2HTR1AADRA2A | |
| SCHEMBL9057029 | 0.89 | HDAC6 (0.47) | CA1CA2CHRM2HTR1AADRA2A | |
| SCHEMBL9056969 | 0.89 | CA1 (0.48) | CA1CA2CHRM2HTR1AADRA2A | |
| SCHEMBL27475777 | 0.84 | MEN1 (0.47) | CA1CA2CHRM2HTR1AADRA2A | |
| SCHEMBL27471511 | 0.83 | HDAC6 (0.41) | CA1CA2CHRM2HTR1AADRA2A | |
| SCHEMBL27470535 | 0.83 | HDAC6 (0.44) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL9055755 | 0.81 | CHRM2 (0.50) | CA1CA2CHRM2HTR1AADRA2A | |
| SCHEMBL27489204 | 0.79 | HDAC6 (0.47) | CA1CA2CHRM2HTR1AADRA2A | |
| SCHEMBL7408065 | 0.77 | HDAC6 (0.47) | CA1CA2CHRM2HTR1AADRA2A | |
| SCHEMBL27471510 | 0.77 | CA1 (0.44) | CA1CA2CHRM2HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1166169-A | Heterocyclic compounds, useful as allosteric effectors at muscarinic receptors | SANKYO CO (JP) | 1997-11-26 | — | — | CN | disclosed |