SCHEMBL27489240

SCHEMBL27489240

Nc1ccccc1-c1c(-c2cccc3ccccc23)ccc2cc3ccccc3cc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.44
HSD17B10 Q99714 4/20 0.44
HPGD P15428 3/20 0.44
KEAP1 Q14145 2/20 0.44
CYP3A4 P08684 2/20 0.44
TSHR P16473 1/20 0.44
HIF1A Q16665 2/20 0.41
CYP1B1 Q16678 1/20 0.41
CES1 P23141 1/20 0.41
DNMT1 P26358 1/20 0.40
PIM1 P11309 1/20 0.39
HPRT1 P00492 1/20 0.39
ANPEP P15144 1/20 0.38
DHFR P00374 1/20 0.38
GPR84 Q9NQS5 1/20 0.38
KDM4E B2RXH2 2/20 0.37
GAA P10253 2/20 0.37
CYP1A2 P05177 2/20 0.37
NPC1 O15118 1/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7709939 0.90 ALDH1A1 (0.46) ALDH1A1HSD17B10HPGDKEAP1CYP3A4
SCHEMBL243631 0.89 ALDH1A1 (0.48) ALDH1A1HSD17B10HPGDTSHRHIF1A
SCHEMBL28916630 0.87 ALDH1A1 (0.47) ALDH1A1HSD17B10HPGDTSHRHIF1A
SCHEMBL27569161 0.87 ALDH1A1 (0.47) ALDH1A1HSD17B10HPGDTSHRHIF1A
SCHEMBL21617935 0.87 DNMT1 (0.49) ALDH1A1HSD17B10HPGDTSHRHIF1A
SCHEMBL30302657 0.84 ALDH1A1 (0.48) ALDH1A1HSD17B10HPGDTSHRHIF1A
SCHEMBL30332669 0.83 CES1 (0.45) ALDH1A1HSD17B10HPGDTSHRHIF1A
SCHEMBL29410607 0.81 CES1 (0.44) ALDH1A1HSD17B10HPGDCYP3A4TSHR
SCHEMBL3869266 0.81 CES1 (0.44) ALDH1A1HSD17B10HPGDCYP3A4TSHR
SCHEMBL30332860 0.81 CES1 (0.44) ALDH1A1HSD17B10HPGDTSHRHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100528831-C Organic electroluminescent device and phenylenediamine derivative IDEMITSU KOSAN CO (JP) 2009-08-19 CN disclosed
CN-101096344-A Organic electroluminescent device and phenylenediamine derivative IDEMITSU KOSAN CO (JP) 2008-01-02 CN disclosed
CN-1733700-A Organic electroluminescent device and phenylenediamine derivative IDEMITSU KOSAN CO (JP) 2006-02-15 CN disclosed
CN-1213127-C Organic electroluminescent device and phenylenediamine derivative IDEMITSU KOSAN CO (JP) 2005-08-03 CN disclosed
CN-1277626-A Organic electroluminescent device and phenylenediamine derivative IDEMITSU KOSAN CO (JP) 2000-12-20 CN disclosed