Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | PPARD | Q03181 | 7/20 | 0.41 |
| ▸ | PPARA | Q07869 | 7/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28835927 | 0.98 | NOD1 (0.49) | NOD1AKR1B1PLA2G10PLA2G2CGPR84 | |
| SCHEMBL2247417 | 0.98 | NOD1 (0.49) | NOD1AKR1B1PLA2G10PLA2G2CGPR84 | |
| SCHEMBL2244646 | 0.97 | NOD1 (0.51) | NOD1PLA2G10PLA2G2CGPR84PPARG | |
| SCHEMBL30812451 | 0.97 | NOD1 (0.51) | NOD1PLA2G10PLA2G2CGPR84PPARG | |
| SCHEMBL2251083 | 0.97 | NOD1 (0.51) | NOD1PLA2G10PLA2G2CGPR84PPARG | |
| Hydrochloric Acid SCHEMBL29178099 | 0.95 | NOD1 (0.50) | NOD1PLA2G10PLA2G2CGPR84PPARG | |
| Ammonia Solution, Strong SCHEMBL7072310 | 0.87 | NOD1 (0.57) | NOD1AKR1B1PLA2G10PLA2G2CGPR84 | |
| Ammonia Solution, Strong SCHEMBL9940081 | 0.87 | NOD1 (0.57) | NOD1AKR1B1PLA2G10PLA2G2CGPR84 | |
| Ammonia Solution, Strong SCHEMBL4416355 | 0.87 | NOD1 (0.57) | NOD1AKR1B1PLA2G10PLA2G2CGPR84 | |
| SCHEMBL2242492 | 0.86 | FOLH1 (0.41) | NOD1PLA2G10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1102382-C | Preparation and methods for the treatment of T cell mediated diseases | YEDA RES & DEV (IL) | 2003-03-05 | — | — | CN | disclosed |
| CN-1193907-A | Preparation and methods for the treatment of T cell mediated diseases | YEDA RES & DEV (IL) | 1998-09-23 | — | — | CN | disclosed |