Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 2/20 | 0.49 |
| ▸ | BID | P55957 | 3/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.45 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.45 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.45 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.45 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.45 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8398437 | 0.87 | ALOX5 (0.63) | ALOX5PTGS2TYRBIDMCL1 | |
| SCHEMBL574313 | 0.87 | ALOX5 (0.63) | ALOX5PTGS2TYRBIDMCL1 | |
| SCHEMBL8401876 | 0.87 | TYR (0.54) | ALOX5TYRBIDMCL1BCL2L1 | |
| SCHEMBL574556 | 0.87 | TYR (0.54) | ALOX5TYRBIDMCL1BCL2L1 | |
| SCHEMBL16051902 | 0.85 | ALOX5 (0.65) | ALOX5PTGS2TYRBIDMCL1 | |
| SCHEMBL573232 | 0.85 | TYR (0.51) | ALOX5TYRBIDMCL1BCL2L1 | |
| SCHEMBL11164405 | 0.81 | ALOX5 (0.57) | ALOX5PTGS2TYRBIDMCL1 | |
| SCHEMBL573894 | 0.81 | TYR (0.52) | ALOX5TYRMEN1TP53CYP3A4 | |
| SCHEMBL10926251 | 0.75 | ALOX5 (0.68) | ALOX5PTGS2TYRBIDMCL1 | |
| SCHEMBL11618297 | 0.75 | ALOX5 (0.68) | ALOX5PTGS2TYRBIDMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1124922-A | Use of natural products and related synthetic compounds for the treatment of cardiovascular diseases | UNIV SYDNEY (AU) | 1996-06-19 | — | — | CN | disclosed |