Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 4/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27505400 | 0.90 | BIRC5 (0.41) | TMPRSS4P2RX1CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL27523064 | 0.87 | P2RX1 (0.38) | TMPRSS4P2RX1CYP3A4P2RX7P2RX4 | |
| SCHEMBL27523776 | 0.86 | CETP (0.40) | CYP2C9ALOX5APFEN1CETP | |
| SCHEMBL27413033 | 0.84 | IDO1 (0.40) | TMPRSS4P2RX1CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL27412369 | 0.83 | PDE3B (0.34) | P2RX1GCGR | |
| SCHEMBL27537513 | 0.77 | P2RX1 (0.38) | TMPRSS4P2RX1CYP3A4P2RX7P2RX4 | |
| SCHEMBL27480024 | 0.76 | P2RX7 (0.38) | P2RX7ALOX5APFEN1CETP | |
| SCHEMBL5756140 | 0.74 | TMPRSS4 (0.40) | TMPRSS4P2RX1CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL27505399 | 0.73 | TMPRSS4 (0.41) | TMPRSS4P2RX1CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL27421301 | 0.72 | TRPV1 (0.38) | CYP2C9CYP2C19ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1226803-A | Diphenyl heterocycles as potassium channel modulators | BRISTOL MYERS SQUIBB CO (US) | 1999-08-25 | — | — | CN | claimed |
| CN-1116287-C | Diphenyl heterocycles as potassium channel modulators | BRISTOL MYERS SQUIBB CO (US) | 2003-07-30 | — | — | CN | disclosed |
| CN-1226803-A | Diphenyl heterocycles as potassium channel modulators | BRISTOL MYERS SQUIBB CO (US) | 1999-08-25 | — | — | CN | disclosed |