Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 10/20 | 0.67 |
| ▸ | ACE | P12821 | 9/20 | 0.67 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.39 |
| ▸ | FNTA | P49354 | 2/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8027482 | 0.92 | MME (0.80) | MMEACECTSSCTSKTACR1 | |
| SCHEMBL8027261 | 0.90 | MME (0.80) | MMEACECTSSCTSKTACR1 | |
| SCHEMBL8017444 | 0.90 | MME (0.83) | MMEACECTSSCTSKTACR1 | |
| SCHEMBL27547831 | 0.90 | MME (0.83) | MMEACECTSSCTSKTACR1 | |
| SCHEMBL8027294 | 0.88 | MME (0.83) | MMEACECTSSCTSKTACR1 | |
| SCHEMBL8451438 | 0.88 | MME (0.83) | MMEACECTSSCTSKTACR1 | |
| SCHEMBL27464096 | 0.86 | MME (0.68) | MMEACECTSKTACR1CPA1 | |
| SCHEMBL27463687 | 0.86 | MME (0.52) | MMEACEPSEN1PSEN2APH1B | |
| SCHEMBL27444759 | 0.85 | MME (0.57) | MMEACEMMP9PSEN1PSEN2 | |
| SCHEMBL27444756 | 0.85 | MME (0.57) | MMEACEMMP9PSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1138321-A | 1, 3-dialkyl urea derivative with hydrocarbon group | SANTAN PHARMACEUTICAL CO LTD (JP) | 1996-12-18 | — | — | CN | disclosed |