Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 11/20 | 0.83 |
| ▸ | ACE | P12821 | 11/20 | 0.83 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8451438 | 1.00 | MME (0.83) | MMEACETACR1CPA1ACE2 | |
| SCHEMBL8017444 | 0.94 | MME (0.83) | MMEACETACR1CPA1ACE2 | |
| SCHEMBL27547831 | 0.94 | MME (0.83) | MMEACETACR1CPA1ACE2 | |
| SCHEMBL8017267 | 0.91 | MME (1.00) | MMEACECPA1ACE2MMP9 | |
| SCHEMBL27464096 | 0.91 | MME (0.68) | MMEACETACR1CPA1ACE2 | |
| SCHEMBL8027482 | 0.89 | MME (0.80) | MMEACETACR1CPA1ACE2 | |
| SCHEMBL27489673 | 0.88 | MME (0.67) | MMEACETACR1CPA1ACE2 | |
| SCHEMBL8027498 | 0.87 | MME (0.75) | MMEACETACR1CPA1ACE2 | |
| SCHEMBL8451466 | 0.87 | MME (0.88) | MMEACECPA1ACE2MMP9 | |
| SCHEMBL8027410 | 0.87 | MME (0.88) | MMEACECPA1ACE2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| CN-1138321-A | 1, 3-dialkyl urea derivative with hydrocarbon group | SANTAN PHARMACEUTICAL CO LTD (JP) | 1996-12-18 | — | — | CN | disclosed |