Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 7/20 | 0.40 |
| ▸ | ALPL | P05186 | 5/20 | 0.40 |
| ▸ | CA12 | O43570 | 5/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GRN | P28799 | 1/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL343503 | 0.83 | GRN (0.53) | CA9CA12SMYD3NAMPTKDM4E | |
| Hydrochloric Acid SCHEMBL6378087 | 0.81 | GRN (0.51) | CA9CA12SMYD3NAMPTKDM4E | |
| SCHEMBL27462320 | 0.79 | GRN (0.68) | CA9ALPLKDM4EGRNSORT1 | |
| SCHEMBL27464512 | 0.76 | ALPL (0.55) | CA9ALPLCA12HCAR3ALOX15 | |
| SCHEMBL1423106 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL23780332 | 0.74 | ALPL (0.53) | CA9ALPLCA12HCAR3ALOX15 | |
| Ethane SCHEMBL4702984 | 0.74 | ALPL (0.53) | CA9ALPLCA12HCAR3ALOX15 | |
| SCHEMBL8508457 | 0.71 | GRN (0.55) | CA9CA12SMYD3NAMPTKDM4E | |
| SCHEMBL1431995 | 0.71 | ALPL (0.54) | CA9ALPLCA12HCAR3ALOX15 | |
| SCHEMBL28138855 | 0.71 | SMYD3 (0.42) | CA9CA12SMYD3NAMPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1234693-C | Indazol compound for inhibiting protein kinase and medicine composition and their application | AGOURON PHARMA (US) | 2006-01-04 | — | — | CN | disclosed |
| CN-1495171-A | Indazol compound for inhibiting protein kinase and medicine composition and their application | ������ҩ������˾ | 2004-05-12 | — | — | CN | disclosed |
| CN-1137884-C | Indazole compounds and pharmaceutical compositions that inhibit protein kinases and methods of use thereof | ������ҩ������˾ | 2004-02-11 | — | — | CN | disclosed |
| CN-1374950-A | Indazole compounds and pharmaceutical compositions for inhibiting protein kinases and their use | AGOURON PHARMACETUICALS INC (US) | 2002-10-16 | — | — | CN | disclosed |