SCHEMBL27489698

SCHEMBL27489698

CC(N)C(=O)N(C)CCO

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.42
CHRNB4 P30926 1/20 0.42
CHRNA3 P32297 1/20 0.42
CHRNA4 P43681 1/20 0.42
DPP4 P27487 3/20 0.37
MAPT P10636 1/20 0.36
NOS3 P29474 1/20 0.32
NOS1 P29475 1/20 0.32
NOS2 P35228 1/20 0.32
ARG1 P05089 1/20 0.31
CNR1 P21554 1/20 0.31
DPP9 Q86TI2 1/20 0.31
LTA4H P09960 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34463642 1.00 CHRNB2 (0.42) CHRNB2CHRNB4CHRNA3CHRNA4DPP4
SCHEMBL2745900 0.83 DPP4 (0.56) CHRNB2CHRNB4CHRNA3CHRNA4DPP4
SCHEMBL19502904 0.82 DPP4 (0.37) CHRNB2CHRNA4DPP4MAPTNOS3
SCHEMBL19502834 0.82 DPP4 (0.37) CHRNB2CHRNA4DPP4MAPTNOS3
SCHEMBL4546666 0.81 CHRNB2 (0.44) CHRNB2CHRNB4CHRNA3CHRNA4DPP4
SCHEMBL4324459 0.79 CA12 (0.32) CHRNB2CHRNB4CHRNA3CHRNA4DPP4
SCHEMBL26535305 0.79 CHRNB2 (0.43) CHRNB2CHRNB4CHRNA3CHRNA4DPP4
SCHEMBL14679290 0.77 CHRNB2 (0.42) CHRNB2CHRNB4CHRNA3CHRNA4DPP4
SCHEMBL19308262 0.77 CHRNB2 (0.42) CHRNB2CHRNB4CHRNA3CHRNA4DPP4
SCHEMBL5514707 0.77 CHRNB2 (0.42) CHRNB2CHRNB4CHRNA3CHRNA4DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1114637-C Reactive amine catalysts for use in polyurethane polymers CROMPUTONS CORP (US) 2003-07-16 CN disclosed