Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | RRM1 | P23921 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5404631 | 0.83 | PIM1 (0.60) | KDM4ENPC1RAB9AKMT2AGAA | |
| SCHEMBL5404629 | 0.83 | PIM1 (0.60) | KDM4ENPC1RAB9AKMT2AGAA | |
| SCHEMBL2220800 | 0.83 | TRIM24 (0.58) | KDM4ENPC1RAB9AKMT2AGAA | |
| SCHEMBL29950729 | 0.83 | TRIM24 (0.58) | KDM4ENPC1RAB9AKMT2AGAA | |
| SCHEMBL2811213 | 0.78 | HTT (0.59) | KDM4ENPC1RAB9AKMT2AGAA | |
| SCHEMBL29415445 | 0.78 | HTT (0.59) | KDM4ENPC1RAB9AKMT2AGAA | |
| SCHEMBL29264080 | 0.74 | DNA2 (0.47) | KDM4ENPC1RAB9AKMT2AGAA | |
| SCHEMBL29264078 | 0.74 | DNA2 (0.47) | KDM4ENPC1RAB9AKMT2AGAA | |
| SCHEMBL30946589 | 0.74 | DNA2 (0.52) | NPC1KMT2AGAAHTTHPGD | |
| SCHEMBL27174908 | 0.74 | DNA2 (0.52) | NPC1KMT2AGAAHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1213029-C | Process for the preparation of (3-cyano-1H-indol-7-yl) (4-(4-fluorophenethyl)piperazin-1-yl)-methanone and salts thereof | MERCH PATENT GMBH (DE) | 2005-08-03 | — | — | CN | disclosed |
| CN-1487923-A | Process for the preparation of (3-cyano-1H-indol-7-yl) (4- (4-fluorophenethyl) piperazin-1-yl) -methanone and salts thereof | Ĭ��ר���ɷ�����˾ | 2004-04-07 | — | — | CN | disclosed |