Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BCL9 | O00512 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27490556 | 0.85 | KDM4E (0.44) | KDM4ELMNAALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL9871396 | 0.80 | MAPT (0.56) | MAPTKDM4ELMNAALDH1A1GAA | |
| SCHEMBL10347130 | 0.76 | MAPT (0.55) | MAPTKDM4ELMNAALDH1A1GAA | |
| SCHEMBL7138665 | 0.73 | MAPT (0.64) | MAPTKDM4ELMNAALDH1A1GAA | |
| SCHEMBL5692340 | 0.72 | MAPT (0.66) | MAPTKDM4ELMNAALDH1A1GAA | |
| SCHEMBL5692343 | 0.72 | MAPT (0.66) | MAPTKDM4ELMNAALDH1A1GAA | |
| SCHEMBL27915343 | 0.71 | MAPT (0.54) | MAPTKDM4ELMNAALDH1A1GAA | |
| SCHEMBL4279296 | 0.71 | MAPT (0.57) | MAPTKDM4ELMNAALDH1A1GAA | |
| SCHEMBL7139968 | 0.70 | MAPT (0.67) | MAPTKDM4ELMNAALDH1A1GAA | |
| SCHEMBL11431545 | 0.70 | MAPT (0.53) | MAPTKDM4ELMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1205687-A | Tyrosin-derivate as alpha-V-integrin inhibitors | MERCK PATENT GES MIT BESCHR KT (DE) | 1999-01-20 | — | — | CN | disclosed |