Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | TRPM7 | Q96QT4 | 1/20 | 0.37 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | INHA | P05111 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | TRPV2 | Q9Y5S1 | 1/20 | 0.36 |
| ▸ | ICMT | O60725 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27511944 | 0.84 | PPARA (0.43) | PPARGPPARAHTR2AMAPTRARB | |
| SCHEMBL6579381 | 0.82 | ALDH1A1 (0.35) | TRPV1LMNACYP1A2POLBMAPT | |
| SCHEMBL6579376 | 0.82 | ALDH1A1 (0.35) | TRPV1LMNACYP1A2POLBMAPT | |
| SCHEMBL27491014 | 0.78 | PPARA (0.47) | PPARGPPARAHTR2ARARBKAT8 | |
| SCHEMBL27511943 | 0.78 | PPARA (0.47) | PPARGPPARAHTR2ARARBKAT8 | |
| SCHEMBL27511939 | 0.76 | PPARA (0.37) | PPARGPPARATRPV1CYP1A2CYP3A4 | |
| SCHEMBL27476014 | 0.76 | PPARA (0.38) | PPARGPPARATRPV1CYP1A2CYP3A4 | |
| SCHEMBL27491013 | 0.75 | PPARA (0.39) | PPARGPPARALMNACYP1A2CYP3A4 | |
| SCHEMBL6582084 | 0.74 | MEN1 (0.39) | PPARALMNACYP1A2POLBMAPT | |
| SCHEMBL6582092 | 0.74 | MEN1 (0.39) | PPARALMNACYP1A2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1161337-C | Chinolinelone derivative, its prepn. method and antiabnormal reaction agent | ���ձ���ī��ѧ��ҵ��ʽ���� | 2004-08-11 | — | — | CN | disclosed |
| CN-1221738-A | Chinolinelone derivative, its prepn. method and antiabnormal reaction agent | DAINIPPON INK & CHEMICALS (JP) | 1999-07-07 | — | — | CN | disclosed |