Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 2/20 | 0.32 |
| ▸ | RARB | P10826 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.30 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.30 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27492048 | 0.93 | PPARA (0.36) | PPARAPPARGKAT8LTB4R2 | |
| SCHEMBL27476016 | 0.91 | PPARA (0.43) | PPARAPPARGRARARARBKAT8 | |
| SCHEMBL27475378 | 0.90 | PPARA (0.33) | PPARAPPARG | |
| SCHEMBL27511939 | 0.88 | PPARA (0.37) | PPARAPPARGRARARARBALDH1A1 | |
| SCHEMBL27491346 | 0.86 | PPARA (0.40) | PPARAPPARGRARARARBALDH1A1 | |
| SCHEMBL27496205 | 0.86 | PPARA (0.40) | PPARAPPARGRARARARBKAT8 | |
| SCHEMBL27473238 | 0.82 | PPARA (0.39) | PPARAPPARGRARARARBALDH1A1 | |
| SCHEMBL27556121 | 0.82 | PPARA (0.41) | PPARAPPARGRARARARBALDH1A1 | |
| SCHEMBL27472802 | 0.82 | PPARA (0.41) | PPARAPPARGALDH1A1KAT8LTB4R2 | |
| SCHEMBL27473239 | 0.81 | PPARA (0.37) | PPARAPPARGALDH1A1KAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1161337-C | Chinolinelone derivative, its prepn. method and antiabnormal reaction agent | ���ձ���ī��ѧ��ҵ��ʽ���� | 2004-08-11 | — | — | CN | disclosed |
| CN-1221738-A | Chinolinelone derivative, its prepn. method and antiabnormal reaction agent | DAINIPPON INK & CHEMICALS (JP) | 1999-07-07 | — | — | CN | disclosed |