Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27476016 | 0.90 | PPARA (0.43) | PPARAPPARGKAT8STAT3PLA2G4B | |
| SCHEMBL27491704 | 0.87 | PPARA (0.43) | PPARAPPARGKAT8DRD2OPRM1 | |
| SCHEMBL27551069 | 0.87 | KDM4E (0.37) | ALDH1A1NPC1RAB9ALTB4R2 | |
| SCHEMBL27491012 | 0.84 | PDK1 (0.37) | ALDH1A1STAT3LTB4R2 | |
| SCHEMBL27476015 | 0.83 | LTB4R (0.37) | ALDH1A1NPC1RAB9ALTB4R2 | |
| SCHEMBL27490291 | 0.82 | PPARA (0.35) | PPARAPPARGKAT8ALDH1A1LTB4R2 | |
| SCHEMBL27492048 | 0.81 | PPARA (0.36) | PPARAPPARGKAT8LTB4R2 | |
| SCHEMBL27491346 | 0.81 | PPARA (0.40) | PPARAPPARGKAT8ALDH1A1TP53 | |
| SCHEMBL27491344 | 0.81 | PPARA (0.37) | PPARAPPARGKAT8ALDH1A1PLA2G4B | |
| SCHEMBL27473238 | 0.81 | PPARA (0.39) | PPARAPPARGKAT8ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1161337-C | Chinolinelone derivative, its prepn. method and antiabnormal reaction agent | ���ձ���ī��ѧ��ҵ��ʽ���� | 2004-08-11 | — | — | CN | disclosed |
| CN-1221738-A | Chinolinelone derivative, its prepn. method and antiabnormal reaction agent | DAINIPPON INK & CHEMICALS (JP) | 1999-07-07 | — | — | CN | disclosed |