Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6123137 | 0.72 | AKR1B1 (0.32) | MEN1KMT2A | |
| SCHEMBL942698 | 0.66 | POLB (0.40) | MEN1KMT2A | |
| SCHEMBL1427350 | 0.66 | POLB (0.40) | MEN1KMT2A | |
| SCHEMBL9241243 | 0.64 | POLB (0.39) | MEN1KMT2A | |
| SCHEMBL2320721 | 0.63 | POLB (0.38) | MEN1KMT2A | |
| SCHEMBL14839741 | 0.63 | GPR84 (0.53) | MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL606836 | 0.63 | POLB (0.38) | MEN1KMT2A | |
| SCHEMBL603685 | 0.63 | POLB (0.38) | MEN1KMT2A | |
| SCHEMBL1261859 | 0.62 | — | — | |
| Hexane SCHEMBL7079135 | 0.61 | AKR1B1 (0.58) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1220490-C | Application of piperazine oxirane derivative in preparation of medicine for inducing tumor cell death | HITACHI CHEMICAL CO LTD (JP) | 2005-09-28 | — | — | CN | disclosed |
| CN-1212623-A | Method for inducing death of neoplastic cells using piperazine oxirane derivatives | HITACHI CHEMICAL CO LTD (JP) | 1999-03-31 | — | — | CN | disclosed |