Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 4/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | MAP3K12 | Q12852 | 6/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27490490 | 0.81 | PTGS2 (0.50) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL27339504 | 0.69 | PTGS1 (0.68) | PTGS2PTGS1CYP2C9PDPK1 | |
| SCHEMBL27507517 | 0.68 | PTGS2 (0.63) | PTGS2PTGS1CYP2C9PDPK1 | |
| SCHEMBL27531781 | 0.66 | PTGS2 (0.61) | PTGS2PTGS1CYP2C9PDPK1 | |
| SCHEMBL27431078 | 0.66 | PTGS2 (0.69) | PTGS2PTGS1CYP2C9PDPK1 | |
| SCHEMBL27318326 | 0.65 | PTGS2 (0.66) | PTGS2PTGS1CYP2C9PDPK1HDAC3 | |
| SCHEMBL27323859 | 0.65 | PTGS2 (0.57) | PTGS2PTGS1CYP2C9PDPK1 | |
| SCHEMBL27339501 | 0.65 | PTGS1 (0.71) | PTGS2PTGS1CYP2C9PDPK1 | |
| SCHEMBL27321222 | 0.65 | CYP2C9 (0.57) | PTGS2PTGS1CYP2C9PDPK1HDAC3 | |
| SCHEMBL8924318 | 0.64 | PTGS2 (0.63) | NR3C2PTGS2PTGS1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1203589-A | novel compounds | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-12-30 | — | — | CN | disclosed |