Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 5/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.53 |
| ▸ | PPARA | Q07869 | 8/20 | 0.49 |
| ▸ | PPARD | Q03181 | 5/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5004593 | 0.90 | BLM (0.67) | BLMESR1ESR2CA2CAMK2A | |
| SCHEMBL11529482 | 0.85 | PPARA (0.49) | BLMPPARAPPARDPPARG | |
| SCHEMBL3270164 | 0.85 | PPARA (0.55) | PPARAPPARDPPARG | |
| SCHEMBL11527067 | 0.84 | PPARA (0.54) | PPARAPPARDPPARGMEN1KMT2A | |
| SCHEMBL28106001 | 0.83 | BLM (0.54) | BLMESR1ESR2PPARAPPARD | |
| SCHEMBL11596247 | 0.79 | BLM (0.67) | BLMESR1ESR2CA2CAMK2A | |
| SCHEMBL19183326 | 0.78 | PPARA (0.46) | BLMPPARAPPARDPPARGMEN1 | |
| SCHEMBL5343038 | 0.78 | BLM (0.56) | BLMESR1ESR2CA2CAMK2A | |
| SCHEMBL13809480 | 0.77 | BLM (0.65) | BLMESR1ESR2CA2CAMK2A | |
| SCHEMBL5329866 | 0.76 | BLM (0.64) | BLMESR1ESR2CA2CAMK2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1211359-C | Novel phenylalkoxy-phenyl derivatives | ASTRAZENECA AB (SE) | 2005-07-20 | — | — | CN | disclosed |
| CN-1433401-A | Novel phenylalkoxy-phenyl derivatives | ASTRAZENECA AB (SE) | 2003-07-30 | — | — | CN | disclosed |
| CN-1312795-A | Novel 3-arylpropionic acid derivatives and analogs thereof | ASTRA ZENECA AKTIEBOLAG (SE) | 2001-09-12 | — | — | CN | disclosed |