Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.49 |
| ▸ | PPARD | Q03181 | 6/20 | 0.49 |
| ▸ | PPARG | P37231 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27490673 | 0.85 | BLM (0.61) | PPARAPPARDPPARGBLM | |
| SCHEMBL3270164 | 0.85 | PPARA (0.55) | PPARAPPARDPPARGMMP8SMN1; SMN2 | |
| SCHEMBL11527067 | 0.84 | PPARA (0.54) | PPARAPPARDPPARG | |
| SCHEMBL24440180 | 0.82 | HPGD (0.46) | PPARAPPARDHPGDCTBP2SRD5A2 | |
| SCHEMBL11531882 | 0.82 | HPGD (0.50) | PPARAPPARDPPARGHPGDCTBP2 | |
| SCHEMBL4457891 | 0.79 | BLM (0.47) | PPARAPPARGHPGDBLMCTBP2 | |
| SCHEMBL19183326 | 0.78 | PPARA (0.46) | PPARAPPARDPPARGHPGDBLM | |
| SCHEMBL14672757 | 0.77 | HPGD (0.43) | HPGDBLMCTBP2SRD5A2SMN1; SMN2 | |
| SCHEMBL27880060 | 0.76 | BLM (0.46) | HPGDBLMCTBP2SRD5A2SMN1; SMN2 | |
| SCHEMBL15314315 | 0.76 | ALDH1A1 (0.46) | HPGDBLMCTBP2SRD5A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166131-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANTIARTHRITIC AGENT | HEXACHIMIE SOCIETE ANONYME (FR) | 1979-08-28 | — | — | US | disclosed |