SCHEMBL27491122

SCHEMBL27491122

NCc1ccc(OC(=O)CCCC(=O)O)cc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.47
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
HTT P42858 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TPSAB1 Q15661 2/20 0.44
PRSS1 P07477 2/20 0.43
PRSS2 P07478 2/20 0.43
PRSS3 P35030 2/20 0.43
EGFR P00533 2/20 0.43
ERBB2 P04626 2/20 0.43
F2 P00734 2/20 0.42
PDE4B Q07343 1/20 0.41
FFAR1 O14842 3/20 0.40
TSHR P16473 1/20 0.40
ST14 Q9Y5Y6 1/20 0.39
LOXL2 Q9Y4K0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27770061 0.93 KMT2A (0.53) KMT2AALDH1A1LMNAMAPTHTT
SCHEMBL27367054 0.90 KMT2A (0.52) KMT2AALDH1A1LMNAMAPTHTT
SCHEMBL27367053 0.86 KMT2A (0.59) KMT2AALDH1A1LMNAMAPTHTT
SCHEMBL5075613 0.84 KMT2A (0.63) KMT2AALDH1A1LMNAMAPTHTT
SCHEMBL28294798 0.83 KMT2A (0.47) KMT2AALDH1A1LMNAMAPTHTT
SCHEMBL27491824 0.83 KMT2A (0.49) KMT2AALDH1A1LMNAMAPTHTT
SCHEMBL6869291 0.83 KMT2A (0.50) KMT2AALDH1A1LMNAMAPTHTT
SCHEMBL7569171 0.80 PRSS1 (0.57) KMT2AALDH1A1LMNAMAPTHTT
SCHEMBL28151715 0.80 KMT2A (0.51) KMT2AALDH1A1LMNAMAPTHTT
SCHEMBL11579542 0.79 L3MBTL1 (0.56) KMT2AALDH1A1LMNAMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1161962-A Sulphonic-acid-amide derivative KONO PHARMACEUTICAL IND K K (JP) 1997-10-15 CN claimed
CN-101490585-B Optical film, method for producing the same, polarizing plate and liquid crystal display device KONICA MINOLTA OPTO INC 2010-11-10 CN disclosed
CN-101490585-A Optical film, method for producing the same, polarizing plate and liquid crystal display device KONICA MINOLTA OPTO INC (JP) 2009-07-22 CN disclosed
CN-1161962-A Sulphonic-acid-amide derivative KONO PHARMACEUTICAL IND K K (JP) 1997-10-15 CN disclosed