Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 14/20 | 0.78 |
| ▸ | ITGB2 | P05107 | 10/20 | 0.78 |
| ▸ | ICAM1 | P05362 | 10/20 | 0.78 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201065 | 1.00 | ITGAL (0.78) | ITGALITGB2ICAM1NPC1RAB9A | |
| SCHEMBL6198130 | 0.95 | ITGAL (0.74) | ITGALITGB2ICAM1NPC1RAB9A | |
| SCHEMBL6198458 | 0.91 | ITGAL (0.80) | ITGALITGB2ICAM1NPC1RAB9A | |
| SCHEMBL27475299 | 0.91 | ITGAL (0.80) | ITGALITGB2ICAM1NPC1RAB9A | |
| SCHEMBL27473967 | 0.91 | ITGAL (0.80) | ITGALITGB2ICAM1NPC1RAB9A | |
| SCHEMBL6196891 | 0.88 | ITGAL (1.00) | ITGALITGB2ICAM1NPC1RAB9A | |
| SCHEMBL27473969 | 0.88 | ITGAL (0.78) | ITGALITGB2ICAM1NPC1RAB9A | |
| SCHEMBL7619124 | 0.88 | ITGAL (0.60) | ITGALITGB2ICAM1NPC1RAB9A | |
| SCHEMBL6195722 | 0.87 | ITGAL (0.82) | ITGALITGB2ICAM1NPC1RAB9A | |
| SCHEMBL27476333 | 0.87 | ITGAL (0.82) | ITGALITGB2ICAM1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1192018-C | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2005-03-09 | — | — | CN | claimed |
| CN-1353691-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-06-12 | — | — | CN | claimed |
| CN-1350520-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-05-22 | — | — | CN | claimed |
| CN-1680338-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2005-10-12 | — | — | CN | disclosed |
| CN-1192018-C | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2005-03-09 | — | — | CN | disclosed |
| CN-1353691-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-06-12 | — | — | CN | disclosed |
| CN-1350520-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-05-22 | — | — | CN | disclosed |