Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 8/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 7/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 7/20 | 0.36 |
| ▸ | ITGAL | P20701 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27473161 | 0.89 | MEN1 (0.38) | KDM4EFKBP1AALDH1A1MEN1KMT2A | |
| SCHEMBL6197945 | 0.89 | ITGAL (0.44) | ITGB2ICAM1ITGAL | |
| SCHEMBL27492724 | 0.88 | KMT2A (0.38) | KDM4EFKBP1AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL27492008 | 0.86 | ITGB2 (0.40) | KDM4EITGB2ICAM1ITGALALDH1A1 | |
| SCHEMBL27475300 | 0.85 | ALDH1A1 (0.43) | KDM4EITGB2ICAM1ITGALALDH1A1 | |
| SCHEMBL6198128 | 0.85 | ITGB2 (0.39) | KDM4EITGB2ICAM1ITGALALDH1A1 | |
| SCHEMBL7620000 | 0.84 | ITGAL (0.47) | KDM4EITGB2ICAM1ITGALALDH1A1 | |
| SCHEMBL6200571 | 0.82 | ITGAL (0.34) | ITGB2ICAM1ITGAL | |
| SCHEMBL6197045 | 0.81 | ITGAL (0.35) | ITGB2ICAM1ITGAL | |
| SCHEMBL6199356 | 0.80 | ITGAL (0.36) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1192018-C | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2005-03-09 | — | — | CN | claimed |
| CN-1353691-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-06-12 | — | — | CN | claimed |
| CN-1350520-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-05-22 | — | — | CN | claimed |
| CN-1680338-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2005-10-12 | — | — | CN | disclosed |
| CN-1192018-C | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2005-03-09 | — | — | CN | disclosed |
| CN-1353691-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-06-12 | — | — | CN | disclosed |
| CN-1350520-A | Anti-inflammatory and immunosuppressive cell adhesion inhibiting compounds | ABBOTT LAB (US) | 2002-05-22 | — | — | CN | disclosed |