Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.62 |
| ▸ | TERT | O14746 | 3/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.58 |
| ▸ | PPARG | P37231 | 3/20 | 0.58 |
| ▸ | PPARD | Q03181 | 3/20 | 0.58 |
| ▸ | PPARA | Q07869 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | FABP4 | P15090 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | GMNN | O75496 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27533398 | 0.98 | FAAH (0.64) | FAAHTERTPTPN1PPARGPPARD | |
| SCHEMBL27602092 | 0.87 | KMT2A (0.56) | PTPN1PPARGPPARDPPARAMAPT | |
| SCHEMBL27752866 | 0.87 | KMT2A (0.56) | PTPN1PPARGPPARDPPARAMAPT | |
| SCHEMBL19621259 | 0.87 | KMT2A (0.56) | PTPN1PPARGPPARDPPARAMAPT | |
| SCHEMBL905583 | 0.87 | KMT2A (0.56) | PTPN1PPARGPPARDPPARAMAPT | |
| SCHEMBL27473710 | 0.87 | KMT2A (0.56) | PTPN1PPARGPPARDPPARAMAPT | |
| Hydrochloric Acid SCHEMBL30294041 | 0.85 | KMT2A (0.54) | PTPN1PPARGPPARDPPARAMAPT | |
| Hydrochloric Acid SCHEMBL28305557 | 0.85 | KMT2A (0.54) | PTPN1PPARGPPARDPPARAMAPT | |
| SCHEMBL29195405 | 0.83 | FAAH (0.58) | FAAHTERTPTPN1PPARGPPARD | |
| SCHEMBL31108096 | 0.83 | FAAH (0.58) | FAAHTERTPTPN1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103025323-A | Pharmaceutical composition having improved solubility of poorly soluble tricyclic derivative compound | JEIL PHARMACEUTICAL CO LTD | 2013-04-03 | — | — | CN | claimed |
| CN-103025323-B | Pharmaceutical composition having improved solubility of poorly soluble tricyclic derivative compound | JE IL PHARMACEUTICAL Co.,Ltd. (KR) | 2014-10-15 | — | — | CN | disclosed |
| CN-103025323-A | Pharmaceutical composition having improved solubility of poorly soluble tricyclic derivative compound | JEIL PHARMACEUTICAL CO LTD | 2013-04-03 | — | — | CN | disclosed |
| CN-1616665-B | Targeted liposome gene delivery | UNIV OF GEORGETOWN | 2010-10-06 | — | — | CN | disclosed |
| CN-1904055-A | Targeted liposome gene delivery | UNIV GEORGETOWN (US) | 2007-01-31 | — | — | CN | disclosed |
| CN-1616665-A | Targeted liposome gene delivery | UNIV OF GEORGETOWN (US) | 2005-05-18 | — | — | CN | disclosed |
| CN-1191094-C | Targeted liposome gene delivery | UNIV OF GEORGETOWN (US) | 2005-03-02 | — | — | CN | disclosed |
| CN-1286630-A | Targeted liposome gene delivery | UNIV OF GEORGETOWN (US) | 2001-03-07 | — | — | CN | disclosed |