Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.55 |
| ▸ | MAOB | P27338 | 7/20 | 0.41 |
| ▸ | MAOA | P21397 | 5/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aniline SCHEMBL4694521 | 0.80 | TSHR (0.55) | TSHRMAOBMAOACYP19A1HSD17B10 | |
| Aniline SCHEMBL28296543 | 0.80 | TSHR (0.55) | TSHRMAOBMAOACYP19A1HSD17B10 | |
| Biphenyl SCHEMBL3258858 | 0.79 | ALDH1A1 (0.50) | TSHRHSD17B10TAAR1HTTALDH1A1 | |
| Aniline SCHEMBL27877636 | 0.78 | TSHR (0.69) | TSHRMAOBMAOACYP19A1HSD17B10 | |
| Aniline SCHEMBL28143089 | 0.78 | TSHR (0.69) | TSHRMAOBMAOACYP19A1HSD17B10 | |
| Benzene SCHEMBL28999580 | 0.78 | TSHR (0.75) | TSHRHTTALDH1A1CYP2C19 | |
| Aniline SCHEMBL22528486 | 0.78 | TSHR (0.92) | TSHRMAOBMAOACYP19A1HSD17B10 | |
| Benzene SCHEMBL3943034 | 0.78 | TSHR (0.75) | TSHRHTTALDH1A1CYP2C19 | |
| Phenol SCHEMBL11597390 | 0.77 | CA12 (0.58) | TSHRTDP1ALDH1A1CYP2C19CYP1A2 | |
| Allyl Alcohol SCHEMBL11350636 | 0.76 | ALDH1A1 (0.59) | TSHRHSD17B10CYP3A4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1207274-C | Preparation method of 2-alkyl acyl-4-alkylamio phenol | UNIV ZHEJIANG (CN) | 2005-06-22 | — | — | CN | disclosed |
| CN-1475478-A | Preparation method of 2-alkyl acyl-4-alkylamio phenol | 浙江大学 | 2004-02-18 | — | — | CN | disclosed |