Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.63 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.63 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27479119 | 0.94 | MAPK9 (0.63) | MAPK9MAPK10RXFP1LMNAUSP2 | |
| SCHEMBL2421884 | 0.85 | MAPK9 (0.85) | MAPK9MAPK10RXFP1LMNAUSP2 | |
| SCHEMBL27495526 | 0.83 | MAPK9 (0.49) | MAPK9MAPK10LMNASMN1; SMN2MAPT | |
| SCHEMBL27494742 | 0.81 | MAPK9 (0.57) | MAPK9MAPK10RXFP1LMNAUSP2 | |
| SCHEMBL2422088 | 0.80 | MAPK9 (0.81) | MAPK9MAPK10RXFP1LMNAUSP2 | |
| SCHEMBL7447931 | 0.80 | MAPK9 (0.76) | MAPK9MAPK10RXFP1LMNAUSP2 | |
| SCHEMBL27495909 | 0.80 | MAPK9 (0.45) | MAPK9MAPK10MEN1KMT2ABCL2 | |
| SCHEMBL27478299 | 0.79 | MAPK9 (0.46) | MAPK9MAPK10LMNAMEN1KMT2A | |
| SCHEMBL2420683 | 0.79 | MAPK9 (0.85) | MAPK9MAPK10RXFP1LMNAUSP2 | |
| SCHEMBL6439255 | 0.79 | MAPK9 (0.76) | MAPK9MAPK10RXFP1LMNAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1189467-C | Pharmaceutically active sulfonamide derivatives | APPLIED RES SYSTEM ARS HOLDING (AN) | 2005-02-16 | — | — | CN | disclosed |
| CN-1377347-A | Pharmaceutically active sulfonamide derivatives | APPLIED RESEARCH SYSTEMS (NL) | 2002-10-30 | — | — | CN | disclosed |