Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.36 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | CCKBR | P32239 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27560179 | 0.90 | MAPK9 (0.41) | MAPK9MAPK10BCL2BCL2L1TGM2 | |
| SCHEMBL27479501 | 0.87 | MAPK9 (0.47) | MAPK9MAPK10BCL2BCL2L1TGM2 | |
| SCHEMBL2422037 | 0.84 | MAPK9 (0.59) | MAPK9MAPK10BCL2BCL2L1TGM2 | |
| SCHEMBL27495526 | 0.82 | MAPK9 (0.49) | MAPK9MAPK10BCL2BCL2L1TGM2 | |
| SCHEMBL27478701 | 0.82 | CCR2 (0.42) | MEN1KMT2ACCR2 | |
| SCHEMBL27478299 | 0.81 | MAPK9 (0.46) | MAPK9MAPK10BCL2BCL2L1MEN1 | |
| SCHEMBL27494340 | 0.81 | MAPK9 (0.42) | MAPK9MAPK10BCL2BCL2L1TGM2 | |
| SCHEMBL27493170 | 0.80 | MAPK9 (0.45) | MAPK9MAPK10BCL2BCL2L1MEN1 | |
| SCHEMBL27479119 | 0.80 | MAPK9 (0.63) | MAPK9MAPK10BCL2BCL2L1TGM2 | |
| SCHEMBL27494743 | 0.80 | MAPK9 (0.63) | MAPK9MAPK10BCL2BCL2L1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1189467-C | Pharmaceutically active sulfonamide derivatives | APPLIED RES SYSTEM ARS HOLDING (AN) | 2005-02-16 | — | — | CN | disclosed |
| CN-1377347-A | Pharmaceutically active sulfonamide derivatives | APPLIED RESEARCH SYSTEMS (NL) | 2002-10-30 | — | — | CN | disclosed |