Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TOP2A | P11388 | 2/20 | 0.47 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.47 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1765966 | 0.79 | MGAM (0.65) | MGAMCYP1A2PDGFRBPDGFRACFTR | |
| SCHEMBL3396690 | 0.79 | MGAM (0.65) | MGAMCYP1A2PDGFRBPDGFRACFTR | |
| SCHEMBL19779627 | 0.78 | MGAM (0.54) | MGAMCYP1A2PDGFRBPDGFRACFTR | |
| SCHEMBL28048 | 0.78 | MGAM (1.00) | MGAMCYP1A2PDGFRBPDGFRACFTR | |
| SCHEMBL29362407 | 0.78 | MGAM (1.00) | MGAMCYP1A2PDGFRBPDGFRACFTR | |
| SCHEMBL27062713 | 0.77 | MGAM (0.53) | MGAMCYP1A2PDGFRBPDGFRACFTR | |
| Hydrochloric Acid SCHEMBL9114407 | 0.76 | MGAM (0.96) | MGAMCYP1A2PDGFRBPDGFRACFTR | |
| SCHEMBL28879835 | 0.76 | MGAM (0.61) | MGAMCYP1A2PDGFRBPDGFRACFTR | |
| SCHEMBL610575 | 0.76 | MGAM (0.61) | MGAMCYP1A2PDGFRBPDGFRACFTR | |
| Hydrochloric Acid SCHEMBL1649216 | 0.76 | MGAM (0.96) | MGAMCYP1A2PDGFRBPDGFRACFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1216064-C | Process for preparing 6-o-alkenyl-substituted erythromycin derivatives | ABBOTT LAB (US) | 2005-08-24 | — | — | CN | claimed |
| CN-1379780-A | Process for preparing 6-o-alkenyl-substituted erythromycin derivatives | ABBOTT LAB (US) | 2002-11-13 | — | — | CN | claimed |
| CN-114957086-A | Synthesis method and application of N-trifluoromethylsulfonyl phthalimide | 杭州师范大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-100355734-C | Preparation of quinoline-substituted carbonate and carbamate derivatives | ABBOTT LAB (US) | 2007-12-19 | — | — | CN | disclosed |
| CN-1217934-C | Process for the preparation of quinoline-substituted carbonate and carbamate derivatives | ABBOTT LAB (US) | 2005-09-07 | — | — | CN | disclosed |
| CN-1663952-A | Preparation of quinoline-substituted carbonate and carbamate derivatives | ABBOTT LAB (US) | 2005-09-07 | — | — | CN | disclosed |
| CN-1216064-C | Process for preparing 6-o-alkenyl-substituted erythromycin derivatives | ABBOTT LAB (US) | 2005-08-24 | — | — | CN | disclosed |
| CN-1379780-A | Process for preparing 6-o-alkenyl-substituted erythromycin derivatives | ABBOTT LAB (US) | 2002-11-13 | — | — | CN | disclosed |
| CN-1370148-A | Process for the preparation of quinoline-substituted carbonate and carbamate derivatives | ABBOTT LAB (US) | 2002-09-18 | — | — | CN | disclosed |