SCHEMBL27495271

SCHEMBL27495271

O=c1cc(C(F)(F)F)[nH]c(=O)n1-c1cc(Oc2ccccc2O)c(Cl)cc1F

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BCAT1 P54687 20/20 0.66
BCAT2 O15382 18/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7017337 0.89 BCAT1 (0.67) BCAT1BCAT2
SCHEMBL7020343 0.88 BCAT1 (0.66) BCAT1BCAT2
SCHEMBL7021038 0.86 BCAT1 (0.73) BCAT1BCAT2
SCHEMBL3240485 0.86 BCAT1 (0.62) BCAT1BCAT2
SCHEMBL7022834 0.85 BCAT1 (0.79) BCAT1BCAT2
SCHEMBL7019548 0.85 BCAT1 (0.62) BCAT1BCAT2
SCHEMBL3264126 0.85 BCAT1 (0.60) BCAT1BCAT2
SCHEMBL3240477 0.85 BCAT1 (0.60) BCAT1BCAT2
SCHEMBL7019427 0.84 BCAT1 (0.59) BCAT1BCAT2
SCHEMBL13842893 0.82 BCAT1 (0.59) BCAT1BCAT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1276912-C Uracil compounds and use thereof SUMITOMO CHEMICAL CO (JP) 2006-09-27 CN disclosed
CN-1572786-A Uracil compounds and use thereof SUMITOMO CHEMICAL CO (JP) 2005-02-02 CN disclosed
CN-1187340-C Uracil compound and use thereof SUMITOMO CHEMICAL CO (JP) 2005-02-02 CN disclosed
CN-1303852-A Uracil compound and use thereof SUMITOMO CHEMICAL CO (JP) 2001-07-18 CN disclosed