Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL10610825 | 0.81 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2MAPTSLC22A2SLC22A1 | |
| Biphenyl SCHEMBL323849 | 0.81 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2L3MBTL1MAPTSLC22A2 | |
| Biphenyl SCHEMBL11796483 | 0.79 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2L3MBTL1MAPTSLC22A2 | |
| Biphenyl SCHEMBL11764850 | 0.79 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2L3MBTL1MAPTSLC22A2 | |
| Bromobenzene SCHEMBL27868508 | 0.78 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2MAPTTP53MAPK1 | |
| Biphenyl SCHEMBL967556 | 0.78 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2L3MBTL1MAPTSLC22A2 | |
| Biphenyl SCHEMBL10584306 | 0.77 | ALDH1A1 (0.75) | ALDH1A1SMN1; SMN2MAPTSLC22A2SLC22A1 | |
| Biphenyl SCHEMBL4840882 | 0.75 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2L3MBTL1MAPTSLC22A2 | |
| Biphenyl SCHEMBL7043290 | 0.75 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2L3MBTL1MAPTSLC22A2 | |
| Biphenyl SCHEMBL8328818 | 0.75 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2L3MBTL1MAPTSLC22A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1208323-C | Alpha-substituted carboxylic acid derivatives | SANKYO CO (JP) | 2005-06-29 | — | — | CN | disclosed |
| CN-1353694-A | Alpha-substituted carboxylic acid derivatives | SANKYO CO (JP) | 2002-06-12 | — | — | CN | disclosed |