Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL27496972

N.O=[N+]([O-])c1ccncc1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.63
POLB P06746 4/20 0.63
NPC1 O15118 2/20 0.63
RAB9A P51151 2/20 0.63
L3MBTL1 Q9Y468 1/20 0.61
ALDH1A1 P00352 5/20 0.52
LMNA P02545 1/20 0.52
ACHE P22303 1/20 0.48
HSD17B10 Q99714 1/20 0.48
MITF O75030 1/20 0.46
MAPK1 P28482 1/20 0.46
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
GAA P10253 1/20 0.45
CES1 P23141 1/20 0.44
PDE4B Q07343 1/20 0.44
PDE4D Q08499 1/20 0.44
PDE7A Q13946 1/20 0.44
PDE7B Q9NP56 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL545380 0.97
Hydrochloric Acid SCHEMBL27929116 0.95 MAPT (0.63) MAPTPOLBNPC1RAB9AL3MBTL1
SCHEMBL19859330 0.92 MAPT (0.61) MAPTPOLBNPC1RAB9AL3MBTL1
Hydrazine SCHEMBL29186984 0.90 MAPT (0.59) MAPTPOLBNPC1RAB9AL3MBTL1
Pyrazine SCHEMBL27515795 0.86 MAPT (0.65) MAPTPOLBNPC1RAB9AL3MBTL1
Formic Acid SCHEMBL27648380 0.86 MAPT (0.60) MAPTPOLBNPC1RAB9AL3MBTL1
Ethylene Glycol SCHEMBL29186934 0.86 POLB (0.60) MAPTPOLBNPC1RAB9AL3MBTL1
SCHEMBL3447074 0.83 MAPT (0.62) MAPTPOLBNPC1RAB9AL3MBTL1
Ammonia Solution, Strong SCHEMBL27511010 0.80 ALDH1A1 (0.68) ALDH1A1LMNAACHEHSD17B10MAPK1
SCHEMBL2074168 0.80 TSHR (0.50) MAPTPOLBNPC1RAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113307728-B Preparation method of populus canula pheromone 南京蕃茂生物科技有限公司 2022-02-11 CN claimed
CN-114853668-B Synthesis method of 4-pyridine sulfonic acid 南京红太阳生物化学有限责任公司 2023-08-15 CN disclosed
CN-114853668-A Green synthesis method of 4-pyridinesulfonic acid 南京红太阳生物化学有限责任公司 2022-08-05 CN disclosed
CN-113307728-B Preparation method of populus canula pheromone 南京蕃茂生物科技有限公司 2022-02-11 CN disclosed
CN-104311478-B Method for continuously preparing 4-nitropyridine by using microchannel reactor two-step method 南京工业大学 2016-08-17 CN disclosed
CN-1230187-A Bicyclic heteroaromatic compounds as protein tyrosine kinase inhibitors GLAXO GROUP LTD (GB) 1999-09-29 CN disclosed