Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | AS3MT | Q9HBK9 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | F9 | P00740 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5005325 | 0.79 | SRD5A2 (0.61) | MAPTMAPK1TDP1L3MBTL1SRD5A2 | |
| SCHEMBL4998185 | 0.77 | SRD5A2 (0.50) | MAPTMAPK1TDP1L3MBTL1SRD5A2 | |
| SCHEMBL27513302 | 0.77 | SRD5A2 (0.53) | MAPTMAPK1TDP1L3MBTL1SRD5A2 | |
| SCHEMBL12803818 | 0.76 | MAPT (0.45) | MAPTMAPK1TDP1L3MBTL1SRD5A2 | |
| SCHEMBL12260288 | 0.76 | LIPE (0.52) | MAPTMAPK1TDP1L3MBTL1SRD5A2 | |
| SCHEMBL7877768 | 0.76 | SRD5A2 (0.52) | MAPTMAPK1TDP1L3MBTL1SRD5A2 | |
| SCHEMBL12419263 | 0.75 | LIPE (0.48) | MAPTMAPK1TDP1L3MBTL1SRD5A2 | |
| SCHEMBL4997665 | 0.74 | SRD5A2 (0.47) | MAPTMAPK1TDP1L3MBTL1SRD5A2 | |
| SCHEMBL5132653 | 0.72 | MAPT (0.53) | MAPTSRD5A2NPC1RAB9ASRD5A1 | |
| SCHEMBL769005 | 0.72 | RHEB (0.55) | MAPTMAPK1TDP1L3MBTL1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1216864-C | Positive modulators of nicotinic receptor agonists | ASTRAZENECA AB (SE) | 2005-08-31 | — | — | CN | disclosed |
| CN-1387513-A | Positive modulators of nicotinic receptor agonists | ASTRAZENECA AB (SE) | 2002-12-25 | — | — | CN | disclosed |