Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 14/20 | 0.55 |
| ▸ | BRAF | P15056 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | RAF1 | P04049 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.52 |
| ▸ | SMO | Q99835 | 2/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27498393 | 0.89 | MAPK14 (0.55) | MAPK14BRAFALOX15KDM4EALDH1A1 | |
| SCHEMBL27515239 | 0.88 | MAPK14 (0.62) | MAPK14BRAFALOX15KDM4EALDH1A1 | |
| SCHEMBL27483416 | 0.87 | MAPK14 (0.73) | MAPK14BRAFALOX15KDM4EALDH1A1 | |
| SCHEMBL6477729 | 0.85 | MAPK14 (0.74) | MAPK14BRAFALOX15KDM4EALDH1A1 | |
| SCHEMBL27497052 | 0.85 | MAPK14 (0.56) | MAPK14BRAFALOX15KDM4EALDH1A1 | |
| SCHEMBL27498043 | 0.84 | MAPK14 (0.60) | MAPK14BRAFALOX15KDM4EALDH1A1 | |
| SCHEMBL27481232 | 0.84 | MEN1 (0.58) | MAPK14BRAFALOX15KDM4EALDH1A1 | |
| SCHEMBL27526698 | 0.81 | MAPK14 (0.52) | MAPK14BRAFALOX15KDM4EALDH1A1 | |
| SCHEMBL27527556 | 0.81 | MAPK14 (0.75) | MAPK14BRAFALOX15KDM4EALDH1A1 | |
| SCHEMBL27481231 | 0.81 | MEN1 (0.56) | MAPK14BRAFALOX15KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109906224-A | TRIAZOLOPYRIDINE COMPOUNDS AND USES THEREOF | 诺华股份有限公司 | 2019-06-18 | — | — | CN | disclosed |
| CN-109790166-A | imidazopyridine compounds for the treatment of cancer | 诺华股份有限公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-1185211-C | Benzamide derivatives for the treatment of diseases caused by cytokines | ASTRA ZENECA LTD (SE) | 2005-01-19 | — | — | CN | disclosed |