Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 7/20 | 0.59 |
| ▸ | MAPK12 | P53778 | 7/20 | 0.59 |
| ▸ | MAPK11 | Q15759 | 7/20 | 0.59 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ABCC9 | O60706 | 4/20 | 0.43 |
| ▸ | ABCC8 | Q09428 | 4/20 | 0.43 |
| ▸ | KCNJ11 | Q14654 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27498159 | 0.82 | MAPK13 (0.64) | MAPK13MAPK12MAPK11MAPK14HDAC3 | |
| SCHEMBL27497520 | 0.80 | AKR1C3 (0.53) | AKR1C3AKR1C2MAPK1ALDH1A1GAA | |
| SCHEMBL7871444 | 0.80 | PBRM1 (0.51) | MAPK13MAPK12MAPK11MAPK14MAPK1 | |
| SCHEMBL27483181 | 0.80 | MAPK13 (0.64) | MAPK13MAPK12MAPK11MAPK14HDAC3 | |
| SCHEMBL6653033 | 0.80 | MAPK13 (0.76) | MAPK13MAPK12MAPK11MAPK14HDAC3 | |
| SCHEMBL27497517 | 0.78 | MAPK13 (0.62) | MAPK13MAPK12MAPK11MAPK14HDAC3 | |
| SCHEMBL27497519 | 0.77 | MAPK13 (0.61) | MAPK13MAPK12MAPK11MAPK14HDAC3 | |
| SCHEMBL6654792 | 0.77 | MAPK13 (0.68) | MAPK13MAPK12MAPK11MAPK14PTGS1 | |
| SCHEMBL3978775 | 0.75 | MAPK13 (1.00) | MAPK13MAPK12MAPK11MAPK14HDAC3 | |
| SCHEMBL6652827 | 0.74 | MAPK13 (0.73) | MAPK13MAPK12MAPK11MAPK14PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1188388-C | Aminobenzophenones as inhibitors of interleukin and TNF | LEO PHARM PROD LTD (DK) | 2005-02-09 | — | — | CN | disclosed |