Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3198016 | 0.91 | AR (0.43) | SRD5A2MAPTMAPK1HTTLMNA | |
| SCHEMBL30469486 | 0.91 | AR (0.43) | SRD5A2MAPTMAPK1HTTLMNA | |
| SCHEMBL7190381 | 0.88 | PTGS1 (0.41) | PBRM1SRD5A2MAPTMAPK1HTT | |
| SCHEMBL7188882 | 0.87 | PBRM1 (0.57) | PBRM1SRD5A2MAPTMAPK1HTT | |
| SCHEMBL29518166 | 0.82 | CDC25B (0.50) | SRD5A2MAPTHTTLMNAL3MBTL1 | |
| SCHEMBL498590 | 0.82 | CDC25B (0.50) | SRD5A2MAPTHTTLMNAL3MBTL1 | |
| SCHEMBL3658939 | 0.81 | VNN1 (0.60) | SRD5A2ATMTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL11735726 | 0.81 | MEN1 (0.61) | PBRM1SRD5A2MAPTHTTLMNA | |
| SCHEMBL23388266 | 0.80 | VCAM1 (0.53) | SRD5A2MAPTHTTLMNAATM | |
| SCHEMBL27497828 | 0.80 | MAPK13 (0.59) | PBRM1SRD5A2MAPTMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102126994-B | Benzophenone hydrazone derivative and preparation method and application thereof | SINOCHEM LANTIAN CO LTD | 2014-07-09 | — | — | CN | disclosed |
| CN-102126994-A | Benzophenone hydrazone derivative and preparation method and application thereof | SINOCHEM LANTIAN CO LTD | 2011-07-20 | — | — | CN | disclosed |
| US-6313174-B1 | FOR THERAPY AND PROPHYLAXIS OF ASTHMA, ALLERGY, RHEUMATOID ARTHRITIS, SPONDYLOARTHRITIS, GOUT, ATHEROSCLEROSIS, CHRONIC INFLAMMATORY BOWEL DISEASE, PROLIFERATIVE AND INFLAMMATORY SKIN DISORDERS | Leo Pharmaceutical Products Ltd.A/S/ (Løvens kemiske Fabrik Produktionsaktieselskab) (DK) | 2001-11-06 | — | — | US | disclosed |