SCHEMBL27498

SCHEMBL27498

O=C(O)c1ccc(F)cc1

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.85
BAD Q92934 1/20 0.85
TSHR P16473 3/20 0.71
TP53 P04637 1/20 0.71
MITF O75030 1/20 0.65
CES2 O00748 2/20 0.65
CES1 P23141 2/20 0.65
SRD5A2 P31213 2/20 0.60
CA1 P00915 4/20 0.59
CA2 P00918 4/20 0.59
NR4A2 P43354 1/20 0.59
CA12 O43570 1/20 0.57
CA3 P07451 1/20 0.57
TYR P14679 1/20 0.57
DRD1 P21728 1/20 0.57
CA4 P22748 1/20 0.57
CA6 P23280 1/20 0.57
CA5A P35218 1/20 0.57
CA7 P43166 1/20 0.57
CA9 Q16790 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18670950 1.00 BCL2L1 (0.85) BCL2L1BADTSHRTP53MITF
SCHEMBL4570568 1.00 BCL2L1 (0.85) BCL2L1BADTSHRTP53MITF
SCHEMBL11452380 0.97 BCL2L1 (0.81) BCL2L1BADTSHRTP53MITF
Methane SCHEMBL6203577 0.97 BCL2L1 (0.81) BCL2L1BADTSHRTP53MITF
SCHEMBL17332097 0.97 BCL2L1 (0.81) BCL2L1BADTSHRTP53MITF
SCHEMBL17332135 0.97 BCL2L1 (0.81) BCL2L1BADTSHRTP53MITF
Fluoride SCHEMBL10732554 0.97 BCL2L1 (0.81) BCL2L1BADTSHRTP53MITF
Ammonia Solution, Strong SCHEMBL4465466 0.97 BCL2L1 (0.81) BCL2L1BADTSHRTP53MITF
SCHEMBL22734857 0.97 BCL2L1 (0.81) BCL2L1BADTSHRTP53MITF
SCHEMBL10607654 0.97 BCL2L1 (0.81) BCL2L1BADTSHRTP53MITF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7407 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116903866-B Polyvinyl alcohol modified multifunctional powder slump retaining agent and preparation method thereof JIANGSU ARIT NEW MATERIALS CO.,LTD. (CN) 2026-05-26 CN claimed
CN-122084586-A Nanosheet Tb-MOF fluorescence sensor for treating phosphogypsum and Al in red mud3+Application of detection 2026-05-26 CN claimed
CN-122071585-A Preparation method and application of pyrrole boron-based porous conjugated polymer material 中国科学院宁波材料技术与工程研究所 2026-05-22 CN claimed
EP-4743438-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE BENZOTRICHLORIDE COMPOUNDS Aarti Industries Limited (IN) 2026-05-20 EP claimed
CN-122059821-A Method for preparing p-fluorobenzoic acid by oxidizing p-fluorotoluene with hydrogen peroxide under catalysis of composite catalyst 江苏三吉利化工股份有限公司 2026-05-19 CN claimed
CN-122036490-A Method for synthesizing p-fluorobenzoic acid by p-fluorotoluene and oxygen 江苏三吉利化工股份有限公司 2026-05-15 CN claimed
CN-122010702-A Synthesis method for preparing 4,4' -difluorobenzophenone by one-pot domino reaction 江苏三吉利化工股份有限公司 2026-05-12 CN claimed
US-20260126457-A1 METHOD FOR PREDICTING TRANSFECTION EFFICIENCY OF FLUORINATED LIPID NANOPARTICLES USING MULTI-NUCLEAR MAGNETIC RESONANCE INNOVATION ACADEMY FOR PRECISION MEASUREMENT SCIENCE AND TECH CHINESE ACADEMY OF SCIENCES (CN) 2026-05-07 US claimed
EP-4737891-A1 METHOD FOR PREDICTING TRANSFECTION EFFICIENCY OF FLUORINATED LIPID NANOPARTICLES USING NUCLEAR MAGNETIC RESONANCE Innovation Academy for Precision Measurement Science and Technology, CAS (CN) 2026-05-06 EP claimed
EP-4127157-B1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS ENCODIA INC (US) 2026-02-11 EP claimed
EP-0254431-A2 Polyether ketone E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-01-27 EP claimed
EP-0249999-A2 Triazolyl ethyl ethers and fungicides containing them BASF Aktiengesellschaft (DE) 1987-12-23 EP claimed
US-4692447-A HYPOTENSIVE, VASODILATOR, ANTITHROMBOTIC, ANTIAGGREGANT, CYTOPROTECTIVE BOEHRINGER BIOCHEMIA ROBIN, S.P.A. (IT) 1987-09-08 US claimed
US-4668830-A Process for the preparation of compounds containing a difluoromethylene or trifluoromethyl group RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1987-05-26 US claimed
US-4585899-A MANGANESE DIOXIDE CHEM SYSTEMS INC. (US) 1986-04-29 US claimed
US-4585900-A COPPER ACTIVATED YTTRIUM OXIDE CHEM SYSTEMS INC. (US) 1986-04-29 US claimed
EP-0069598-B1 PREPARATION OF AROMATIC KETONES RAYCHEM CORPORATION (a California corporation) (US) 1984-12-19 EP claimed
US-4411975-A TONER AND DEVELOPER FOR ELECTROSTATIC IMAGES XEROX CORPORATION (US) 1983-10-25 US claimed
EP-0069598-A1 Preparation of aromatic ketones RAYCHEM CORPORATION (a California corporation) (US) 1983-01-12 EP claimed
US-4152160-A PHOTOTHERMOGRAPHY, SILVER BEHENATE FUJI PHOTO FILM CO., LTD. (JP) 1979-05-01 US claimed