Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.81 |
| ▸ | BAD | Q92934 | 1/20 | 0.81 |
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | MITF | O75030 | 1/20 | 0.63 |
| ▸ | CES2 | O00748 | 2/20 | 0.62 |
| ▸ | CES1 | P23141 | 2/20 | 0.62 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 4/20 | 0.56 |
| ▸ | CA2 | P00918 | 4/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | TYR | P14679 | 1/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4570568 | 0.97 | BCL2L1 (0.85) | BCL2L1BADTSHRTP53MITF | |
| SCHEMBL27498 | 0.97 | BCL2L1 (0.85) | BCL2L1BADTSHRTP53MITF | |
| SCHEMBL18670950 | 0.97 | BCL2L1 (0.85) | BCL2L1BADTSHRTP53MITF | |
| SCHEMBL11452380 | 0.94 | BCL2L1 (0.81) | BCL2L1BADTSHRTP53MITF | |
| SCHEMBL22734857 | 0.94 | BCL2L1 (0.81) | BCL2L1BADTSHRTP53MITF | |
| SCHEMBL17332135 | 0.94 | BCL2L1 (0.81) | BCL2L1BADTSHRTP53MITF | |
| SCHEMBL11187046 | 0.94 | BCL2L1 (0.81) | BCL2L1BADTSHRTP53MITF | |
| Fluoride SCHEMBL10732554 | 0.94 | BCL2L1 (0.81) | BCL2L1BADTSHRTP53MITF | |
| Ammonia Solution, Strong SCHEMBL4465466 | 0.94 | BCL2L1 (0.81) | BCL2L1BADTSHRTP53MITF | |
| SCHEMBL10607654 | 0.94 | BCL2L1 (0.81) | BCL2L1BADTSHRTP53MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |