Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 2/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6169007 | 0.77 | PTGS1 (0.50) | NPC1RAB9AMEN1KMT2ATP53 | |
| SCHEMBL27517533 | 0.76 | BRD4 (0.49) | NPC1RAB9AMEN1KMT2ATP53 | |
| SCHEMBL6167859 | 0.73 | NPC1 (0.38) | NPC1RAB9AMEN1KMT2ATP53 | |
| SCHEMBL8800658 | 0.73 | HEXA (0.42) | NPC1RAB9AMEN1KMT2ATP53 | |
| SCHEMBL4028141 | 0.71 | PTGS1 (0.45) | NPC1RAB9AMEN1KMT2ATP53 | |
| SCHEMBL10629178 | 0.70 | ESR2 (0.48) | NPC1RAB9AMEN1KMT2ATP53 | |
| SCHEMBL6169852 | 0.70 | MAPK10 (0.46) | NPC1MEN1KMT2AHPGDNPSR1 | |
| Sulfamide SCHEMBL4639248 | 0.70 | PTPN1 (0.46) | MEN1KMT2AHPGDNPSR1PTGS1 | |
| SCHEMBL8479645 | 0.69 | PTGS2 (0.41) | MEN1KMT2AHPGDNPSR1PTGS1 | |
| SCHEMBL8478775 | 0.69 | CHEK1 (0.39) | NPC1RAB9AMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1214790-C | Medicinal composition for treating inflammation | SEARLE & CO (US) | 2005-08-17 | — | — | CN | disclosed |
| CN-1442139-A | Medicinal composition for treating inflammation | SEARLE & CO (US) | 2003-09-17 | — | — | CN | disclosed |