Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27292973 | 0.83 | GAA (0.56) | MEN1KMT2ASMN1; SMN2GAARIPK1 | |
| SCHEMBL29945227 | 0.83 | MEN1 (0.49) | MEN1KMT2ASMN1; SMN2ACHEGAA | |
| SCHEMBL264984 | 0.83 | MEN1 (0.49) | MEN1KMT2ASMN1; SMN2ACHEGAA | |
| Formaldehyde SCHEMBL27699492 | 0.81 | MEN1 (0.49) | MEN1KMT2ASMN1; SMN2ACHEHDAC8 | |
| Bromide SCHEMBL27205498 | 0.81 | MEN1 (0.47) | MEN1KMT2ASMN1; SMN2ACHEGAA | |
| Propionaldehyde SCHEMBL28076693 | 0.81 | MEN1 (0.46) | MEN1KMT2ASMN1; SMN2ACHEGAA | |
| SCHEMBL28058882 | 0.78 | HDAC1 (0.47) | MEN1KMT2ASMN1; SMN2GAAHDAC8 | |
| Methoxymethane SCHEMBL27841631 | 0.77 | MEN1 (0.45) | MEN1KMT2ASMN1; SMN2ACHEGAA | |
| Tert-Butylbenzene SCHEMBL27405309 | 0.77 | CYP2C19 (0.50) | KMT2ASMN1; SMN2ACHEHDAC8HDAC4 | |
| SCHEMBL3407170 | 0.77 | CYP1A2 (0.44) | MEN1KMT2ASMN1; SMN2GAARIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103980184-B | Piperidine compounds, medical composition and its use containing this compound | 爱思开生物制药株式会社 | 2016-08-24 | — | — | CN | disclosed |
| CN-102186840-A | Piperidine compounds, pharmaceutical compositions containing the same and uses thereof | SK HOLDINGS CO LTD | 2011-09-14 | — | — | CN | disclosed |
| CN-1216522-A | Therapeutic agent for diabetes | JAPAN TOBACCO INC (JP) | 1999-05-12 | — | — | CN | disclosed |