Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 8/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.61 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.61 |
| ▸ | ADCY5 | O95622 | 4/20 | 0.56 |
| ▸ | PI4KA | P42356 | 2/20 | 0.56 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.56 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.56 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.56 |
| ▸ | AHCY | P23526 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27499558 | 0.91 | ADORA2A (0.61) | ADORA2AADORA1ADORA2BADCY5PI4KA | |
| SCHEMBL13882135 | 0.82 | ADORA2A (0.66) | ADORA2AADORA1ADORA2BADCY5PI4KA | |
| SCHEMBL13870051 | 0.81 | ADORA2A (0.69) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL11222112 | 0.79 | ADORA2A (0.80) | ADORA2AADORA1ADORA2BADCY5PI4KA | |
| SCHEMBL27713663 | 0.79 | EGFR (0.64) | ADORA2AADORA1ADORA2BADCY5PI4KA | |
| SCHEMBL5038900 | 0.78 | SLC22A6 (0.62) | ADORA2AADORA1ADORA2BADCY5PI4KA | |
| SCHEMBL12922452 | 0.77 | ALDH1A1 (0.62) | ADORA2AADORA1ADORA2BADCY5PI4KA | |
| SCHEMBL11986908 | 0.77 | ALDH1A1 (0.62) | ADORA2AADORA1ADORA2BADCY5PI4KA | |
| Methylglyoxal SCHEMBL6013418 | 0.77 | ADORA2A (0.76) | ADORA2AADORA1ADORA2BADCY5PI4KA | |
| SCHEMBL11986907 | 0.77 | ADORA2A (0.59) | ADORA2AADORA1ADORA2BADCY5PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1234718-C | New macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2006-01-04 | — | — | CN | disclosed |
| CN-1464880-A | New macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2003-12-31 | — | — | CN | disclosed |