Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27500949 | 0.90 | LSS (0.39) | LSSHRH3NPC1RAB9AGAA | |
| SCHEMBL27499031 | 0.90 | LSS (0.39) | LSSNPC1RAB9AGAAALDH1A1 | |
| SCHEMBL27517711 | 0.90 | CYP1A2 (0.41) | LSSNPC1RAB9AGAANAMPT | |
| SCHEMBL27500573 | 0.90 | GAA (0.46) | LSSNPC1RAB9AGAAALDH1A1 | |
| SCHEMBL5043448 | 0.89 | LSS (0.38) | LSSNPC1RAB9AGAAALDH1A1 | |
| SCHEMBL27499635 | 0.87 | CYP1A2 (0.48) | FAAH | |
| SCHEMBL27499947 | 0.81 | LSS (0.41) | LSSALDH1A1NAMPTBCHE | |
| SCHEMBL6448197 | 0.80 | LSS (0.76) | LSSKDM4EMEN1KMT2A | |
| SCHEMBL27579069 | 0.80 | LSS (0.43) | LSSHRH3NPC1RAB9AGAA | |
| SCHEMBL27517388 | 0.79 | LSS (0.38) | LSSRAB9AGAAEPHX2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1231466-C | New piperidine derivatives | HOFFMANN LA ROCHE (CH) | 2005-12-14 | — | — | CN | disclosed |
| CN-1468220-A | New piperidine derivatives | - | 2004-01-14 | — | — | CN | disclosed |