Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 2/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27517711 | 0.90 | CYP1A2 (0.41) | LSSCHRNA7NPC1RAB9AGAA | |
| SCHEMBL27499032 | 0.90 | LSS (0.49) | LSSNPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL27500949 | 0.90 | LSS (0.39) | LSSNPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL27500573 | 0.90 | GAA (0.46) | LSSNPC1RAB9AMGLLALDH1A1 | |
| SCHEMBL5043448 | 0.89 | LSS (0.38) | LSSNPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL27499635 | 0.87 | CYP1A2 (0.48) | MGLL | |
| SCHEMBL7768094 | 0.86 | LSS (0.53) | LSSLMNAL3MBTL1MGLLALDH1A1 | |
| SCHEMBL5045831 | 0.85 | LSS (0.52) | LSSLMNAL3MBTL1MGLLALDH1A1 | |
| SCHEMBL27499947 | 0.81 | LSS (0.41) | LSSLMNAALDH1A1NAMPT | |
| SCHEMBL7768101 | 0.81 | ALDH1A1 (0.41) | LSSLMNAMAPTATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1231466-C | New piperidine derivatives | HOFFMANN LA ROCHE (CH) | 2005-12-14 | — | — | CN | disclosed |
| CN-1468220-A | New piperidine derivatives | - | 2004-01-14 | — | — | CN | disclosed |