Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | SCN1A | P35498 | 3/20 | 0.52 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.52 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.48 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22621474 | 0.97 | MEN1 (0.71) | MEN1KMT2AATMSCN1ASCN2A | |
| SCHEMBL13377166 | 0.95 | MEN1 (0.69) | MEN1KMT2AATMSCN1ASCN2A | |
| SCHEMBL9543892 | 0.93 | KMT2A (0.66) | MEN1KMT2AATMSCN1ASCN2A | |
| SCHEMBL28240607 | 0.86 | MEN1 (0.59) | MEN1KMT2AATMSCN1ASCN2A | |
| SCHEMBL23275566 | 0.86 | MMP9 (0.53) | MEN1KMT2AATMSCN1ASCN2A | |
| SCHEMBL23275563 | 0.85 | MEN1 (0.53) | MEN1KMT2AATMSCN1ASCN2A | |
| SCHEMBL27059523 | 0.82 | MEN1 (0.52) | MEN1KMT2AATMHTTALDH1A1 | |
| SCHEMBL3361977 | 0.82 | MEN1 (0.55) | MEN1KMT2ASCN1ASCN2ASCN3A | |
| SCHEMBL30410538 | 0.81 | ATM (0.53) | MEN1KMT2AATMSCN1ASCN2A | |
| SCHEMBL5987325 | 0.81 | MEN1 (0.53) | MEN1KMT2ASCN1ASCN2ASCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1226886-A | Arylcycloalkane carboxylic acid esters, their use, pharmaceutical compositions and process for their preparation | PHARMACIA & UPJOHN AB (SE) | 1999-08-25 | — | — | CN | disclosed |