Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | TOP2A | P11388 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.58 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.49 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27561066 | 0.89 | KDM4E (0.61) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8775506 | 0.86 | KDM4E (0.64) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL9023266 | 0.85 | KDM4E (0.63) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL9023258 | 0.85 | KDM4E (0.63) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL27486246 | 0.83 | DPP4 (0.55) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9215771 | 0.82 | KDM4E (0.66) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL27500527 | 0.82 | KDM4E (0.61) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9150447 | 0.81 | KDM4E (0.68) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL27520584 | 0.81 | KDM4E (0.62) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL27520550 | 0.81 | KDM4E (0.61) | KDM4EALDH1A1LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1184221-C | New quinaldinic acid derivative with 7-(7-aminomethyl-5-azaspiro [2,4] heplane) substituent and its preparation method | INST OF MEDICINAL BIOLOG TECHN (CN) | 2005-01-12 | — | — | CN | claimed |
| CN-1184221-C | New quinaldinic acid derivative with 7-(7-aminomethyl-5-azaspiro [2,4] heplane) substituent and its preparation method | INST OF MEDICINAL BIOLOG TECHN (CN) | 2005-01-12 | — | — | CN | disclosed |
| CN-1400209-A | New quinaldinic acid derivative with 7-(7-aminomethyl-5-azaspiro [2,4] heplane) substituent and its preparation method | INST OF MEDICINAL BIOLOG TECHN (CN) | 2003-03-05 | — | — | CN | disclosed |