Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.51 |
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.44 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27484168 | 0.89 | DPP4 (0.61) | DPP4CHRM2DRD1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL27554040 | 0.88 | DPP4 (0.60) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL8775460 | 0.86 | DPP4 (0.64) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL27500528 | 0.83 | KDM4E (0.61) | LMNAKDM4EHSD17B10CYP2C9ALDH1A1 | |
| SCHEMBL9437323 | 0.83 | DPP4 (0.58) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL27486245 | 0.82 | DPP4 (0.57) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL28745952 | 0.82 | DPP4 (0.63) | DPP4CHRM2DRD1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL27521147 | 0.81 | DPP4 (0.62) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9379622 | 0.81 | DPP4 (0.54) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9181492 | 0.81 | DPP4 (0.54) | DPP4CHRM2DRD1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1184221-C | New quinaldinic acid derivative with 7-(7-aminomethyl-5-azaspiro [2,4] heplane) substituent and its preparation method | INST OF MEDICINAL BIOLOG TECHN (CN) | 2005-01-12 | — | — | CN | claimed |
| CN-1184221-C | New quinaldinic acid derivative with 7-(7-aminomethyl-5-azaspiro [2,4] heplane) substituent and its preparation method | INST OF MEDICINAL BIOLOG TECHN (CN) | 2005-01-12 | — | — | CN | disclosed |
| CN-1400209-A | New quinaldinic acid derivative with 7-(7-aminomethyl-5-azaspiro [2,4] heplane) substituent and its preparation method | INST OF MEDICINAL BIOLOG TECHN (CN) | 2003-03-05 | — | — | CN | disclosed |