Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 6/20 | 0.57 |
| ▸ | F10 | P00742 | 14/20 | 0.57 |
| ▸ | F2 | P00734 | 10/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.57 |
| ▸ | PROC | P04070 | 4/20 | 0.57 |
| ▸ | F9 | P00740 | 3/20 | 0.57 |
| ▸ | KLK1 | P06870 | 1/20 | 0.57 |
| ▸ | CFH | P08603 | 1/20 | 0.56 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31678809 | 0.88 | KLKB1 (0.70) | KLKB1F10F2PRSS1PRSS2 | |
| SCHEMBL27536938 | 0.88 | KLKB1 (0.70) | KLKB1F10F2PRSS1PRSS2 | |
| SCHEMBL27519105 | 0.86 | F10 (0.51) | KLKB1F10F2PRSS1PRSS2 | |
| SCHEMBL27519261 | 0.78 | F2 (0.58) | KLKB1F10F2PRSS1PRSS2 | |
| SCHEMBL29286939 | 0.78 | F10 (0.58) | KLKB1F10F2PRSS1PRSS2 | |
| SCHEMBL29286937 | 0.78 | KLKB1 (0.58) | KLKB1F10F2PRSS1PRSS2 | |
| SCHEMBL27499211 | 0.77 | F2 (0.57) | KLKB1F10F2PRSS1PRSS2 | |
| SCHEMBL27499212 | 0.77 | F2 (0.56) | KLKB1F10F2PRSS1PRSS2 | |
| SCHEMBL27528955 | 0.74 | F2 (0.53) | KLKB1F10F2PRSS1PRSS2 | |
| SCHEMBL4586256 | 0.74 | KLKB1 (0.65) | KLKB1F10CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1246847-A | Nitrogen containing heteroaromatics as factor Xa inhibitors | DU PONT MERCK PHARMA (US) | 2000-03-08 | — | — | CN | claimed |
| CN-1246847-A | Nitrogen containing heteroaromatics as factor Xa inhibitors | DU PONT MERCK PHARMA (US) | 2000-03-08 | — | — | CN | disclosed |