Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371804 | 0.89 | NPC1 (0.50) | NPC1RAB9AHTTHPGDMEN1 | |
| SCHEMBL27449625 | 0.74 | TSHR (0.50) | NPC1ALDH1A1CYP3A4HPGDLMNA | |
| SCHEMBL27519801 | 0.74 | MEN1 (0.48) | NPC1RAB9AHTTALDH1A1CYP3A4 | |
| SCHEMBL777261 | 0.73 | NPC1 (0.53) | NPC1RAB9AHTTHPGDMEN1 | |
| SCHEMBL29436920 | 0.73 | NPC1 (0.53) | NPC1RAB9AHTTHPGDMEN1 | |
| SCHEMBL127127 | 0.73 | NPC1 (0.53) | NPC1RAB9AHTTHPGDMEN1 | |
| SCHEMBL28735227 | 0.71 | NPC1 (0.49) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL101601 | 0.71 | TSHR (0.63) | NPC1RAB9AALDH1A1HPGDKMT2A | |
| SCHEMBL248052 | 0.71 | KMT2A (0.53) | NPC1RAB9AHTTHPGDMEN1 | |
| SCHEMBL29702037 | 0.71 | TSHR (0.63) | NPC1RAB9AALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1108656-A | N-azinyl-N'-(HET)arylsulphonyl-ureas | BAYER AG (DE) | 1995-09-20 | — | — | CN | disclosed |