Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SCN1A | P35498 | 2/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | PTPRF | P10586 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549828 | 0.80 | CHRM2 (0.59) | KMT2ASCN1ASCN2ASCN3AALDH1A1 | |
| Hydrochloric Acid SCHEMBL8556272 | 0.79 | CHRM2 (0.58) | KMT2ASCN1ASCN2ASCN3AALDH1A1 | |
| SCHEMBL8594005 | 0.77 | MEN1 (0.51) | KMT2ASCN1ASCN2ASCN3AMAPT | |
| SCHEMBL8625052 | 0.76 | SCN1A (0.53) | KMT2ASCN1ASCN2ASCN3AALDH1A1 | |
| SCHEMBL8551089 | 0.76 | CARM1 (0.57) | KMT2AALDH1A1CYP3A4CYP2D6MAPT | |
| Hydrochloric Acid SCHEMBL8554706 | 0.75 | KMT2A (0.58) | KMT2AALDH1A1CYP3A4CYP2D6MAPT | |
| SCHEMBL28878770 | 0.75 | GBA1 (0.41) | CA1CA2CA4CA9 | |
| SCHEMBL8550092 | 0.74 | PTPRF (0.45) | SCN1ASCN2ASCN3AMAPTCHRNA7 | |
| SCHEMBL10518314 | 0.72 | OPRD1 (0.43) | SCN1ASCN2ASCN3AALDH1A1 | |
| SCHEMBL8623727 | 0.72 | MAPT (0.52) | KMT2ASCN1ASCN2ASCN3AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1183768-A | Benzyl piepridine derivs as pharmaceutical agents | HOFFMANN LA ROCHE (CH) | 1998-06-03 | — | — | CN | claimed |