Valeric Acid

Valeric Acid

SCHEMBL27502000

CCCCC(=O)O.O=C(O)C(F)(F)F

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.61
GPR84 Q9NQS5 7/20 0.58
PPARG P37231 7/20 0.58
PPARD Q03181 7/20 0.58
PPARA Q07869 7/20 0.58
HDAC11 Q96DB2 5/20 0.58
TSHR P16473 4/20 0.58
PTPN1 P18031 3/20 0.58
ALDH1A1 P00352 2/20 0.58
TLR2 O60603 2/20 0.58
TDP1 Q9NUW8 2/20 0.58
FABP4 P15090 2/20 0.58
KMT2A Q03164 2/20 0.58
SLC22A6 Q4U2R8 1/20 0.58
SLC22A8 Q8TCC7 1/20 0.58
MEN1 O00255 1/20 0.58
ESR1 P03372 1/20 0.58
ALOX15 P16050 1/20 0.58
PDE4A P27815 1/20 0.58
PDE3A Q14432 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexanoate SCHEMBL27386332 0.93 AKR1B1 (0.73) AKR1B1GPR84PPARGPPARDPPARA
Valeric Acid SCHEMBL30248951 0.92 AKR1B1 (0.52) AKR1B1GPR84PPARGPPARDPPARA
Octanoic Acid SCHEMBL30776782 0.91 GPR84 (0.74) AKR1B1GPR84PPARGPPARDPPARA
Octanoic Acid SCHEMBL28493038 0.91 GPR84 (0.74) AKR1B1GPR84PPARGPPARDPPARA
Decanoic Acid SCHEMBL11296360 0.91 GPR84 (0.74) AKR1B1GPR84PPARGPPARDPPARA
Nonanoate SCHEMBL23043798 0.91 GPR84 (0.74) AKR1B1GPR84PPARGPPARDPPARA
Nonanoate SCHEMBL23043748 0.91 GPR84 (0.74) AKR1B1GPR84PPARGPPARDPPARA
Trifluoroacetic Acid SCHEMBL28779288 0.91 GPR84 (0.74) AKR1B1GPR84PPARGPPARDPPARA
Heptanoate SCHEMBL28577565 0.91 GPR84 (0.74) AKR1B1GPR84PPARGPPARDPPARA
Myristic Acid SCHEMBL11293987 0.91 GPR84 (0.74) AKR1B1GPR84PPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108779108-A 3- (2,3- dihydro -1H- indenes -5- bases) propanoic derivatives and their purposes as NRF2 conditioning agents 葛兰素史密斯克莱知识产权发展有限公司 2018-11-09 CN claimed
CN-108137557-A Nrf2 modulators 葛兰素史密斯克莱知识产权发展有限公司 2018-06-08 CN claimed
CN-1265645-A Urokinase inhibitors ABBOTT LAB (US) 2000-09-06 CN claimed
CN-107427699-A For treating the KDM1A inhibitor of disease 伊美格生物科学公司 2017-12-01 CN disclosed
CN-102822154-B Heteroarylcarboxylicacid acid ester derivative AJINOMOTO CO.,INC. (JP) 2016-06-01 CN disclosed
CN-105102468-A C-3 alkyl and alkenyl modified betulinic acid derivatives for the treatment of HIV BRISTOL MYERS SQUIBB CO 2015-11-25 CN disclosed
CN-1972916-B Cinnamide compounds EISAI R&D MAN CO LTD 2013-03-27 CN disclosed
CN-102822154-A Heteroarylcarboxylic acid ester derivative AJINOMOTO KK 2012-12-12 CN disclosed
CN-101723900-B Cinnamide compounds EISAI R&D MAN CO LTD 2012-08-22 CN disclosed
CN-101400657-B Polycyclic cinnamamide derivative ESAI R & D MAN CO LTD 2012-05-30 CN disclosed
CN-101723900-A Cinnamide compounds EISAI R&D MAN CO LTD 2010-06-09 CN disclosed
CN-100577657-C Amorphous form of cinnamide compound EISAI R&D MAN CO LTD 2010-01-06 CN disclosed
CN-101448797-A Heterocyclic type cinnamamide derivative EISAI R&D MAN CO LTD (JP) 2009-06-03 CN disclosed
CN-101400657-A Polycyclic cinnamamide derivative ESAI R & D MAN CO LTD (JP) 2009-04-01 CN disclosed
CN-1972916-A Cinnamide compounds EISAI R&D MAN CO LTD (JP) 2007-05-30 CN disclosed
CN-1201454-A Meta-guanidino, ureido, thioureido or azacyclic aminobenzoic acid derivatives as integrin antagonists SEARLE & CO (US) 1998-12-09 CN disclosed