Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 7/20 | 0.40 |
| ▸ | MMP3 | P08254 | 7/20 | 0.39 |
| ▸ | MMP9 | P14780 | 6/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 2/20 | 0.36 |
| ▸ | FNTB | P49356 | 2/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29666118 | 0.88 | PTGS1 (0.45) | PTGS1SLC7A11MMP1ACEFNTA | |
| SCHEMBL30811198 | 0.82 | MMP1 (0.44) | PTGS1SLC7A11MMP1MMP3MMP9 | |
| SCHEMBL27501940 | 0.81 | SLC7A5 (0.52) | MMP1MMP3MMP9MMP2 | |
| SCHEMBL7049300 | 0.81 | SLC7A5 (0.52) | MMP1MMP3MMP9MMP2 | |
| SCHEMBL30853669 | 0.77 | DPP4 (0.52) | PTGS1MMP1MMP3MMP9CA2 | |
| SCHEMBL29360299 | 0.77 | DPP4 (0.45) | PTGS1MMP1MMP3MMP9CA2 | |
| SCHEMBL6791478 | 0.76 | MME (0.51) | PTGS1SLC7A11ACEFNTAFNTB | |
| SCHEMBL30128682 | 0.76 | MME (0.51) | PTGS1SLC7A11ACEFNTAFNTB | |
| SCHEMBL6791475 | 0.76 | MME (0.51) | PTGS1SLC7A11ACEFNTAFNTB | |
| SCHEMBL11325497 | 0.76 | PTGS1 (0.52) | PTGS1SLC7A11ACEFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1193978-A | Peptidyl compounds and their therapeutic use as inhibitors of metalloproteases | CHIROSCIENCE LTD (GB) | 1998-09-23 | — | — | CN | disclosed |